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InChi: InChI=1S/C19H35BrO8/c1-2-4-21-6-8-23-10-12-25-14-16-27-18-19-28-17-15-26-13-11-24-9-7-22-5-3-20/h1H
Thailanstatin A exerts effects via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the spliceosome and shows low-nM to sub-nM IC50s against multiple cancer cell lines
Chemical Name: (2S)-2-(2-{[(2S
MK 0893 is an inhibitor of both glucagon receptor and IGF-1R with IC50 values of 6
Trabectedin D3 Size:Contact [email protected] for quotation InChi: InChI=1S/C19H35BrO8/c1-2-4-21-6-8-23-10-12-25-14-16-27-18-19-28-17-15-26-13-11-24-9-7-22-5-3-20/h1HTrabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF 7 and MDA MB 453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer
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