N-piperidine Ibrutinib hydrochloride Catalog No.:M30823-C ClH/c1-21-17(14-18(26)22(2)19(21)27)20-9-11-23(12-13-25)10-3-4-15-5-7-16(8-6-15)24(28)29

ClH/c1-21-17(14-18(26)22(2)19(21)27)20-9-11-23(12-13-25)10-3-4-15-5-7-16(8-6-15)24(28)29

6)7)68-60(84)52-53(77)34(2)32-70(52)63(86)50(36(4)73)66-59(83)51(55(79)54(78)41-19-23-43(74)24-20-41)67-58(82)47-30-44(75)33-69(47)62(85)49(35(3)72)65-57(46)81/h11-26

with some indication of a possible accumulation of heavier precursor molecules

5% was equally efficacious as Vancomycin (VAN) in a methicillin-resistant S

N-piperidine Ibrutinib hydrochloride Catalog No.:M30823-C ClH/c1-21-17(14-18(26)22(2)19(21)27)20-9-11-23(12-13-25)10-3-4-15-5-7-16(8-6-15)24(28)29N piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51. 0 and 30. 7 nM for WT BTK and C481S BTK, respectively. N piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY 133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7. 9 nM. Product information CAS Number: