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InChiKey: FAZZYPIBZBGQSH-UHFFFAOYSA-N
ADX47273 increased extracellular signal-regulated kinase and cAMP-responsive element-binding protein phosphorylation in hippocampus and prefrontal cortex
including thrombin and factor Xa
Schering began patient enrollment in phase III studies in May
Brivanib 142-70 InChiKey: FAZZYPIBZBGQSH-UHFFFAOYSA-NBrivanib is the hydrolyzed form of Brivanib alaninate, which is a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Product information CAS
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