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TRPV2 (transient receptor potential vanilloid type 2) antagonist (IC50 = 0
Smiles: O=C1CN(CCN1CC1=CC=CC=C1C(F)(F)F)C1C=NNC(=O)C=1Cl
2% inhibition at 4 and 8 µM
8aR)-8a-hydroxy-4a-methyl-8-methylidene-decahydronaphthalen-2-yl]prop-2-enoic acid
AMG 837 hemicalcium - CAS# 1291087-14-3 amine hydrobromide TRPV2 (transient receptor potential vanilloidAMG 837 hemicalcium is a potent, orally bioavailable and partial agonist of GPR40 FFA1. AMG 837 hemicalcium inhibits specific [3H]AMG 837 binding at the human FFA1 receptor with a pIC50 of 8. 13. AMG 837 hemicalcium could enhance insulin secretion and lower glucose levels in rodents. Product information CAS Number: 1291087 14 3 Molecular Weight: 457. 47 Formula: C52H40CaF6O6 Chemical Name: calcium bis((3S) 3 (4 {[4' (trifluoromethyl) [1,1' biphenyl] 3
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