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D-Trimannuronic acid can be used for the research of pain and vascular dementia
It can inhibit oncogenic RAS signaling and suppress in vitro and in vivo proliferation of human pancreatic ductal adenocarcinoma cells that are dependent on oncogenic KRAS
InChi: InChI=1S/2C26H21F3O3
Formula: C14H15F2N3S
VU0364770 hydrochloride Size:Contact [email protected] for quotation D-Trimannuronic acid can be usedVU0364770 hydrochloride is a selective and potent positive allosteric modulator (PAM) of mGlu4. VU0346770 hydrochloride exhibits EC50s of 290 nM and 1. 1 M at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 hydrochloride exhibits antagonist activity at mGlu5 with a potency of 17. 9 M and PAM activity at mGlu6 with a potency of 6. 8 M. VU0364770 hydrochloride also possesses activity at MAO with Ki values of 8. 5 and 0. 72 M for human MAO A
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