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In LPS-induced acute lung inflammation
IV-361 exhibits excellent HCT-116 cell growth inhibitory activity (GI50≤100 nM)
2-dimethyl-2H
CAS Number: 518-69-4
FIIN-1 ide IV-A In LPS-induced acute lung inflammationFIIN 1 is a potent, irreversible, selective FGFR inhibitor. FIIN 1 binds to FGFR1 2 3 4 and Flt1 4 with Kds of 2. 8 6. 9 5. 4 120 nM and 32 120 nM respectively. The biochemical IC50s of FIIN 1 are 9. 2, 6. 2, 11. 9, and 189 nM against FGFR1 2 3 4, respectively. Product information CAS Number: 1256152 35 8 Molecular Weight: 656. 60 Formula: C32H39Cl2N7O4 Chemical Name: N (3 {[3 (2,6 dichloro 3,5 dimethoxyphenyl) 7 {[4 (diethylamino)butyl]amino} 2 oxo
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