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Dovitinib also stimulates the translocation of phosphorylated Smad1/5/8 into the nucleus and phosphorylation of mitogen-activated protein kinases
ERα and ERβ
Kathawala RJ
PubMed PMID: 25783615
Bisindolylmaleimide X hydrochloride - CAS# 145317-11-9 66045 Dovitinib also stimulates the translocationBisindolylmaleimide X hydrochloride (BIM X hydrochloride), CAS No. 145317 11 9 , is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM. Product information CAS Number: 145317 11 9 Molecular Weight: 460. 96 Formula: C26H25ClN4O2 Synonym: BIM X hydrochloride Ro31 8425 hydrochloride Chemical Name: Bisindolylmaleimide X hydrochloride