Siramesine Catalog No.:M10504-10 Treatment with Danusertib results in

Treatment with Danusertib results in an increase in p53 protein levels and an associated increase in p21 protein

WAY-200070 displays antianxiolytic and antidepressive effects in vivo

VR23: A Quinoline-Sulfonyl Hybrid Proteasome Inhibitor That Selectively Kills Cancer via Cyclin E-Mediated Centrosome Amplification

Smiles: COC1=CC=C(CCC(=O)NC2=NC3=CC=C(Cl)C=C3S2)C=C1OC

Siramesine Catalog No.:M10504-10 Treatment with Danusertib results inSiramesine, also known as Lu 28 179, is a potent sigma 2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress. Product information CAS Number: 147817 50 3 Molecular Weight: 454. 58 Formula: C30H31FN2O Chemical Name: 1' {4 [1 (4 fluorophenyl)