Oclacitinib - CAS# 1208319-26-9 Catalog No.:M9848-2 3-benzoxazol-2-one

3-benzoxazol-2-one

and marketed as Nimbex) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs

InChi: InChI=1S/C20H30N2O5/c1-20(2

Med Hypotheses

Oclacitinib - CAS# 1208319-26-9 Catalog No.:M9848-2 3-benzoxazol-2-oneOclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1 dependent cytokines involved in allergy and