Duocarmycin TM - CAS# 157922-77-5 en HCl Oral administration yields similar concentrations

Oral administration yields similar concentrations of PQR-309 in brain and plasma samples illustrates that PQR-309 readily passes the blood–brain barrier

PMID: 8504141

0810246105

and 200 mg/kg results in mean tumor regression of 92%

Duocarmycin TM - CAS# 157922-77-5 en HCl Oral administration yields similar concentrationsDuocarmycin TM is an exceptionally potent antitumor antibiotic. Duocarmycin TM is a DNA alkylator. Product information CAS Number: 157922 77 5 Molecular Weight: 466. 91 Formula: C25H23ClN2O5 Chemical Name: (1S) 1 (chloromethyl) 3 (5, 6, 7 trimethoxy 1H indole 2 carbonyl) 1H, 2H, 3H benzo[e]indol 5 ol Smiles: COC1=CC2C=C(NC=2C(OC)=C1OC)C(=O)N1C[C@@H](CCl)C2C1=CC(O)=C1C=CC=CC1=2 InChiKey: NRHDGIYFJJUFKN CQSZACIVSA N InChi: InChI=1S C25H23ClN2O5 c1 31 20