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PF-06835919 Catalog No.:M33609-C and prevents DMBA-induced inhibition of

SKU: 60891422143

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Description

and prevents DMBA-induced inhibition of cell growth

3s)-N-ethyl-3-fluoro-3-{3-fluoro-4-[(pyrrolidin-1-yl)methyl]phenyl}cyclobutane-1-carboxamide

6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle

Solubility: H2O : 100 mg/mL (88

PF-06835919 Catalog No.:M33609-C and prevents DMBA-induced inhibition ofPF 06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF 06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to

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