Mutant IDH1-IN-4 terhydrate InChi: InChI=1S/C6H12BrNO2/c1-2-8-6(9)5-10-4-3-7/h2-5H2

InChi: InChI=1S/C6H12BrNO2/c1-2-8-6(9)5-10-4-3-7/h2-5H2

Chemical Name: 1-cyclopentyl-N-[(4

Pitstop-induced inhibition of clathrin TD function acutely interferes with receptor-mediated endocytosis

it is found that closthioamide is highly active against a pathogenic

Mutant IDH1-IN-4 terhydrate InChi: InChI=1S/C6H12BrNO2/c1-2-8-6(9)5-10-4-3-7/h2-5H2Mutant IDH1 IN 4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of 0. 5 M for mutant IDH1 in R132H, HT1080 and U87R132H cells. Product information CAS Number: 1416270 18 2 Molecular Weight: 438. 56 Formula: C25H34N4O3 Chemical Name: 8 cyclopropyl 6 [(3R) 3 cyclopropyl 4 (3 methoxypropanoyl)piperazin 1 yl] 3,3 dimethyl 1H,3H,4H pyrano[3,4 c]pyridine 5 carbonitrile Smiles: