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InChi: InChI=1S/C24H19F3N8O/c1-13-12-14(25)6-7-15(13)20-16-8-9-19(36)35(21-17(26)4-3-5-18(21)27)22(16)33-24(32-20)31-11-10-30-23(28)34-29-2/h3-9
Formula: C23H18N8
with predominant effects on the latter two
Benzyl-PEG7-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
ZX-29 Size:Contact [email protected] for quotation InChi: InChI=1S/C24H19F3N8O/c1-13-12-14(25)6-7-15(13)20-16-8-9-19(36)35(21-17(26)4-3-5-18(21)27)22(16)33-24(32-20)31-11-10-30-23(28)34-29-2/h3-9ZX 29 is a potent and selective ALK inhibitor with an IC50 of 2. 1 nM, 1. 3 nM and 3. 9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively. ZX 29 is inactive against EGFR. ZX 29 induces apoptosis by inducing endoplasmic reticulum (ER) stress and overcomes cell resistance caused by an ALK mutation. ZX 29 also induces protective autophagy and has antitumor effect. Product information CAS Number: 2254805 62 2 Molecular Weight: 518. 03 Formula:
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