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Tegatrabetan (BC2059) treatment disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1) and proteasomal degradation and declines in the nuclear levels of β-catenin
is a potent and selective USP7 inhibitor that was recently identified using an Ub-CHOP reporter assay
CAS Number: 1599477-75-4
PubMed PMID: 23721803
10-Deacetyl-7-xylosyl paclitaxel Size:Solid 2 mg Tegatrabetan (BC2059) treatment disrupts the10 deactyl 7 xylosyl Paclitaxel is a disruptor of microtubules and derivative of paclitaxel that has been found in T. chinensis. It induces the disassembly of pig brain and Physarum microtubules in cell free assays. 10 deactyl 7 xylosyl Paclitaxel inhibits proliferation of, as well as induces cell cycle arrest at the G2 M phase and apoptosis in, PC3 prostate cancer cells. Product information CAS Number: 90332 63 1 Molecular Weight: 943. 98 Formula: