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Smiles: N=C1CCCN1CC1NC(=O)NC(=O)C=1Cl
Solubility: DMSO : ≥ 100 mg/mL (301
24 or 72 h) does not induce apoptosis of HCA-7 and LLC cells
SKF-96365 treatment inhibits the calcium/calmodulin-dependent protein kinase IIγ (CaMKIIγ)/AKT signaling cascade
(S)-Lisofylline Catalog No.:M22422-C Smiles: N=C1CCCN1CC1NC(=O)NC(=O)C=1ClLisofylline (LSF) is a potent anti inflammatory agent. LSF is a chiral metabolite of pentoxifylline . Pentoxifylline is exclusively reduced to (S) LSF in the cytosol when metabolized by isolated human liver cells . In vitro: Lisofylline preserved cell insulin secretion and inhibited DNA damage of islets in the presence of IL 1 . Simultaneous application of LSF and cytokines to INS 1 cells restored insulin secretion, mitochondrial membrane potential,
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