Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact sales@xcessbio.com for quotation Chemical Name: 4-[(1-{[1-({1-[(1-{[5-amino-1-({1-[(1-{[4-carbamimidamido-1-({3-carbamoyl-1-[(1-{[1-({2-carboxy-1-[(1-carboxy-2-hydroxyethyl)carbamoyl]ethyl}carbamoyl)-3-(methylsulfanyl)propyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl)carbamoyl]propyl}carbamoyl)butyl]carbamoyl}-3-carboxypropyl)carbamoyl]-2-phenylethyl}carbamoyl)pentyl]carbamoyl}ethyl)carbamoyl]ethyl}carbamoyl)ethyl]carbamoyl}-2-hydroxypropyl)carbamoyl]-4-(2

Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation Chemical Name: 4-[(1-{[1-({1-[(1-{[5-amino-1-({1-[(1-{[4-carbamimidamido-1-({3-carbamoyl-1-[(1-{[1-({2-carboxy-1-[(1-carboxy-2-hydroxyethyl)carbamoyl]ethyl}carbamoyl)-3-(methylsulfanyl)propyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl)carbamoyl]propyl}carbamoyl)butyl]carbamoyl}-3-carboxypropyl)carbamoyl]-2-phenylethyl}carbamoyl)pentyl]carbamoyl}ethyl)carbamoyl]ethyl}carbamoyl)ethyl]carbamoyl}-2-hydroxypropyl)carbamoyl]-4-(2

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Description

Chemical Name: 4-[(1-{[1-({1-[(1-{[5-amino-1-({1-[(1-{[4-carbamimidamido-1-({3-carbamoyl-1-[(1-{[1-({2-carboxy-1-[(1-carboxy-2-hydroxyethyl)carbamoyl]ethyl}carbamoyl)-3-(methylsulfanyl)propyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl)carbamoyl]propyl}carbamoyl)butyl]carbamoyl}-3-carboxypropyl)carbamoyl]-2-phenylethyl}carbamoyl)pentyl]carbamoyl}ethyl)carbamoyl]ethyl}carbamoyl)ethyl]carbamoyl}-2-hydroxypropyl)carbamoyl]-4-(2

has single-agent antitumor efficacy in triple-negative breast cancer in vitro and in vivo

Procyanidin A1 has antiallergic effects

InChi: InChI=1S/C25H25FN2O3S/c1-16-6-9-18(10-7-16)32(30

Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation Chemical Name: 4-[(1-{[1-({1-[(1-{[5-amino-1-({1-[(1-{[4-carbamimidamido-1-({3-carbamoyl-1-[(1-{[1-({2-carboxy-1-[(1-carboxy-2-hydroxyethyl)carbamoyl]ethyl}carbamoyl)-3-(methylsulfanyl)propyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl)carbamoyl]propyl}carbamoyl)butyl]carbamoyl}-3-carboxypropyl)carbamoyl]-2-phenylethyl}carbamoyl)pentyl]carbamoyl}ethyl)carbamoyl]ethyl}carbamoyl)ethyl]carbamoyl}-2-hydroxypropyl)carbamoyl]-4-(2Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP competitive second generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0. 9 nM and an IC50 of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dimesylate causes double stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti tumor activity. Product information CAS Number: 1234015

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