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CAS Number: 29705-96-2
1 μM in pretreated bladder slices for 60 min
CAS Number: 190967-35-2
Nutlin-3 treatment at 10 μM for 48 hours significantly induces caspase-dependent cell apoptosis by ~45%
3-chloro-5-hydroxy BA Size:Contact [email protected] for quotation CAS Number: 29705-96-23 chloro 5 hydroxy BA is a GPR81 agonist. GPR81 (HCA1) is a member of G protein coupled receptors (GPCRs). GPR81 is predominantly expressed on adipocytes and is activated by the endogenous ligands 2 hydroxypropanoate (lactate). Stimulation of GPR81 in adipose tissue lead to a decrease in the lipolysis of triglycerides by hormone sensitive lipase, which resulted in reduced transport of fatty acids to the liver and a decrease in hepatic triglycerides .
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