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NB-598 is a potent competitive inhibitor of squalene epoxidase (SE)
Proteasome inhibitors: recent advances and new perspectives in medicinal chemistry
InChi: InChI=1S/C22H23ClN2O8/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8
Smiles: CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O
HPK1-IN-3 Catalog No.:M16248-C NB-598 is a potent competitiveHPK1 IN 3 is a potent and selective ATP competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0. 25 nM. HPK1 IN 3 has IL 2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs). Product information Molecular Weight: 490. 45 Formula: C23H22F4N6O2 Chemical Name: 4 ((2 fluoro 6 (trifluoromethyl)phenyl)amino) 2 ((6 methoxy 2 methyl 1, 2, 3, 4 tetrahydroisoquinolin 7 yl)amino)pyrimidine
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