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929007-72-7
InChiKey: CVRXLMUYFMERMJ-UHFFFAOYSA-N
InChi: InChI=1S/C21H19NO5/c23-18-7-3-1-5-14(18)12-22(13-15-6-2-4-8-19(15)24)16-9-10-20(25)17(11-16)21(26)27/h1-11
Formula: C17H18O7
BMS-345541 hydrochloride Size:Solid 2 mg 929007-72-7BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0. 3 and 4. 0 M for IKK and IKK respectively). It attenuates LPS induced cytokine production in vitro and blocks NFB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis. Product information CAS Number: 547757 23 3 Molecular Weight: 291. 78 Formula: C14H18ClN5 Synonym: BMS345541 hydrochloride BMS 345541 hydrochloride BMS 345541