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Cucurbitacin I induces a concentration-dependent decrease in Stat3 expression whereas P-Stat3 is undetectable
modulates Th1 differentiation in CD4(+) T cells from patients with rheumatoid arthritis
Mol Cancer Ther 2014
PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group
Phthalimide-PEG4-PDM-OTBS CT007093 Cucurbitacin I induces a concentration-dependentPhthalimide PEG4 PDM OTBS is a PROTAC linker, which refers to the PEGs composition. Phthalimide PEG4 PDM OTBS can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information Molecular Weight: 536. 73
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