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Chemical Name: 1-hydroxypropane-1
with an ED50 of 13
The trypanosomal pyruvate carrier is found to be rather insensitive to inhibition by alpha-cyano-4-hydroxycinnamate (Ki=17 mM) but can be completely blocked by UK-5099 (Ki=49 microM)
3)57-41(51)49-17-16-48(27-32(49)12-14-43)39-36-13-15-47(38-11-7-9-31-8-5-6-10-35(31)38)29-37(36)44-40(45-39)56-30-33-26-34(28-46(33)4)55-25-24-54-23-22-53-21-20-52-19-18-50/h5-11
7-Hydroxymethotrexate Dihydroxybenzoic acid-d3 Chemical Name: 1-hydroxypropane-17 Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY 14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Product information CAS Number: 5939 37 7 Molecular Weight: 470. 44 Formula: C20H22N8O6 Chemical Name: (2S) 2 [(4 {[(2,4 diamino 7 oxo 7,8 dihydropteridin 6