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A novel BET bromodomain inhibitor
It has minimal activity (IC50 >1 µM) against HDAC4
InChiKey: NVEDPFICKAIHKD-NGYBGAFCSA-N
Molecular Weight: 516
NVS-SM1 - SMN2 Splicing Modulator. CAS# 1562338-42-4 0129 A novel BET bromodomain inhibitorNVS SM1, also known as Branaplam and LMI 070, CAS No. 1562338 42 4, is a highly potent, selective and orally active small molecule SMN2 splicing modulator as a potential treatment for SMA Type 1 (Spinal Muscular Atrophy) . NVS SM1 works by increasing the amount of functional SMN protein produced by the back up gene, SMN2, through modifying its splicing. Product information CAS Number: 1562338 42 4 Molecular Weight: 393. 48 Formula: C22H27N5O2 Synonym:
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