SPL-707 Catalog No.:M23926-C Chemical Name: (2S)-5-tert-butyl-3-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-2

Chemical Name: (2S)-5-tert-butyl-3-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-2

selective and orally available dual inhibitor of pan-PI3-kinase and mTOR with IC50 of 3

000 nM for both A1 and A2A AR and 3 nM for A2B AR subtype in CHO cells expressing recombinant human A1

6-dichlorophenyl)-5-methyl-1

SPL-707 Catalog No.:M23926-C Chemical Name: (2S)-5-tert-butyl-3-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-2SPL 707 is an orally active, selective signal peptide peptidase like 2a (SPPL2a) inhibitor with an IC50 of 77 nM for hSPPL2a. SPL 707 inhibits secretase (IC50=6. 1 M) and SPP (IC50=3. 7 M). SPL 707 has the potential for autoimmune diseases research by targeting B cells and dendritic cells. Product information CAS Number: 2195361 33 0 Molecular Weight: 505. 54 Formula: C27H28FN5O4 Chemical Name: (2S) 2 cyclopropyl N [(9'S) 2',8' dioxo 3',7'