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It is a potent selective inhibitor of the enzyme 11β-HSD1
4(7):e6286
5S)-8-(5-(cyclopropanecarbonyl)pyridin-2-yl)-8-azabicyclo[3
also known as AMD3100
RO-9187 1470 (methanesulfonate) It is a potent selectiveRO 9187 is a potent inhibitor of HCV virus replication in the replicon system (IC(50) = 171 + 12 nM; CC(50) >1 mM). RO 9187 is an excellent substrate for deoxycytidine kinase and is phosphorylated with efficiencies up to 3 fold higher than deoxycytidine. RO 9187 is a new class of antiviral nucleosides with promising preclinical properties as potential medicines for the treatment of HCV infection. Product information CAS Number: 876708 03 1 Molecular