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(Z)-TG003 lesclomol but low activity to RET/PTC1

SKU: 70498004358

4.5
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Description

but low activity to RET/PTC1 rearrangement type with GI50 of 1

CAS Number: 263707-16-0

Isolation of azomycin from Pseudomonas fluorescens

Masutani T

(Z)-TG003 lesclomol but low activity to RET/PTC1TG003 is a potent and ATP competitive Cdc2 like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC. Product information CAS Number: 300801 52 9 Molecular Weight: 249. 33 Formula: C13H15NO2S Chemical Name: (1Z) 1 (3 ethyl 5 methoxy 1, 3 benzothiazol 2 ylidene)propan 2 one Smiles: CC(=O) C=C1\SC2=CC=C(C=C2N\1CC)OC InChiKey: BGVLELSCIHASRV QPEQYQDCSA N

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