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Chemical Name: 1-(2 (Diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride
55)41(53)58-7
Bepotastine besilate is a selective antagonist of histamine 1 (H1) receptor with pIC50 of 5
InChiKey: ITTRLTNMFYIYPA-UHFFFAOYSA-N
BSJ-03-123 rescein Diacetate Chemical Name: 1-(2 (Diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochlorideBSJ 03 123 is a Selective Cdk6 degrader. BSJ 03 123 exploits protein interface determinants to achieve proteome wide selectivity for the degradation of cyclin dependent kinase 6 (CDK6). Pharmacologic CDK6 degradation targets a selective dependency of acute myeloid leukemia cells, and transcriptomics and phosphoproteomics profiling of acute degradation of CDK6 enabled dynamic mapping of its immediate role in coordinating signaling and transcription.
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