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Molecular Weight: 731
but not CCR5−
3-bis(hexadecanoyloxy)propoxy]({2-[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R
ClH/c1-2-30-23(29)17(11-10-16-7-4-3-5-8-16)24-18-15-32-20(19-9-6-12-31-19)13-25(22(18)28)14-21(26)27
NVP-BKM120 Hydrochloride - CAS# 1312445-63-8 Catalog No.:M10296-2 Molecular Weight: 731Buparlisib, also known as BKM120, is an orally bioavailable specific oral inhibitor of the pan class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases with potential antineoplastic activity. PI3K inhibitor BKM120 specifically inhibits class I PIK3 in the PI3K AKT kinase (or protein kinase B) signaling pathway in an ATP competitive manner, thereby inhibiting the production of the secondary messenger phosphatidylinositol 3,4,5 trisphosphate