Rp-8-pCPT-Cyclic GMPS (sodium salt) 078esopitron dihydrochloride Smiles: CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)NC1=CC=C(COC(=O)N(C)CCN(C)C(=O)OC2=CC3=C([C@@H](CN3C(=O)C3=CC4=CC(OC)=C(OC)C(OC)=C4N3)CCl)C3C=C(NC=32)C(=O)OC)C=C1

Smiles: CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)NC1=CC=C(COC(=O)N(C)CCN(C)C(=O)OC2=CC3=C([C@@H](CN3C(=O)C3=CC4=CC(OC)=C(OC)C(OC)=C4N3)CCl)C3C=C(NC=32)C(=O)OC)C=C1

4-bis(3-(3

InChiKey: YOHLRCOPRAVUCJ-UHFFFAOYSA-N

InChiKey: CGYWLLGTCBIGSR-UHFFFAOYSA-N

Rp-8-pCPT-Cyclic GMPS (sodium salt) 078esopitron dihydrochloride Smiles: CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)NC1=CC=C(COC(=O)N(C)CCN(C)C(=O)OC2=CC3=C([C@@H](CN3C(=O)C3=CC4=CC(OC)=C(OC)C(OC)=C4N3)CCl)C3C=C(NC=32)C(=O)OC)C=C1IC50: 18. 3 and 0. 16 M for cGK I and cGK II, respectively. Rp 8 pCPT Cyclic GMPS is a GMP dependent protein kinases (cGKs) inhibitor. Appreciation of cGMP as a distinct intracellular second messenger is reported to be closely followed by an intensive search for effector proteins in various organisms. A cGMP dependent protein kinase (cGK) has been found in arthropods resulting in the eventual isolation of cGK from mammalian tissues. In vitro: Previous