Umbralisib hydrochloride 123346 free base Smiles: C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(O)=O

Smiles: C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(O)=O

CAS Number: 883050-24-6

Formula: C13H13F2N3O3

HSP90 inhibitor CNF2024 specifically blocks active HSP90

Umbralisib hydrochloride 123346 free base Smiles: C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(O)=OUmbralisib hydrochloride (TGR 1202 hydrochloride) is a novel PI3K inhibitor, with IC50 and EC50 of 22. 2 nM and 24. 3 nM, respectively; Umbralisib hydrochloride (TGR 1202 hydrochloride) is also active against CK1, with an EC50 value of 6. 0 M. Product information CAS Number: 1532533 78 0 Molecular Weight: 608. 01 Formula: C31H25ClF3N5O3 Chemical Name: 2 [(1S) 1 {4 amino 3 [3 fluoro 4 (propan 2 yloxy)phenyl] 1H pyrazolo[3,4 d]pyrimidin 1 yl}ethyl] 6