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and reduces the tumor levels in the HCT116 tumor bearing nude BALB/c mice
1045792-66-2
Schonherr C
CAS Number: 1009820-21-6
SD70 - Histone Demethylase JMJD2 Inhibitor. CAS# 332173-89-4 size:2 mg solid and reduces the tumor levelsSD70, CAS No. 332173 89 4, is a potent, selective and cell permeable inhibitor of histone demethylase JMJD2 (KDM4C), identified by phenotypic screening for inhibitors of ligand and genotoxic stress induced translocations in prostate cancer cells. Through Chem seq approach, SD70 was found to inhibit the androgen dependent AR program and prostate cancer cell growth, acting, at least in part, by functionally inhibiting the Jumonji domain containing
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