Pay in 4 interest-free payments of $16.25 Learn more
Ships within 48 hours · Estimated delivery Aug 9 - Aug 14
In R132H-IDH1 glioma xenografts (TS603)
59(12):3099-107
selective and orally bioavailable irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1)
giving growth delays in A431 xenografts exceeding 50 days following oral administration
OG-L002 - LSD1 Inhibitor. CAS# 1357302-64-7 60281 In R132H-IDH1 glioma xenografts (TS603)OG L002, CAS No. 1357302 64 7, is a highly potent and specific inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~20 nM, and has moderate inhibitory activity against monoamine oxidases MAO A and MAO B with IC50 ~1. 38 M and 0. 72M respectively. It potently repressed herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG L002 suppressed primary lytic
US$ 36.00
US$ 10337.00
US$ 59.00
US$ 12.00
US$ 59.00
US$ 36.00
US$ 38.00
US$ 36.00
US$ 36.00
US$ 5419.00
US$ 25.99
US$ 59.00
US$ 109.00