PF-04634817 Catalog No.:M21127-C C6H8O7/c1-20(2)9-4-10-22-12-16(21)17(7-3-8-17)13-5-6-14(18)15(19)11-13

C6H8O7/c1-20(2)9-4-10-22-12-16(21)17(7-3-8-17)13-5-6-14(18)15(19)11-13

Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(N[C@H]2CN(CCCCCCCNC(=O)COC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CCC2)=NC=C1Cl

Smiles: COC1C=C(C=C2SC(=O)NC2=O)C=CC=1OC

interleukin-6 (IL-6)

PF-04634817 Catalog No.:M21127-C C6H8O7/c1-20(2)9-4-10-22-12-16(21)17(7-3-8-17)13-5-6-14(18)15(19)11-13PF 0463481 is a potent and orally active dual CCR2 CCR5 antagonist with comparable human and rodent CCR2 potency (rat IC50=20. 8 nM), and displays 10 20 fold less rodent CCR5 potency (rat IC50=470 nM). PF 0463481 is safe and well tolerated and has the potential for the study of diabetic nephropathy. Product information CAS Number: 1228111 63 4 Molecular Weight: 511. 58 Formula: C25H36F3N5O3 Chemical Name: (3S,4S) 3 methoxy N [(1R,3S) 3 (propan 2 yl) 3