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5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
5 µM concentration in vitro and in cellular assays
It has no apparent toxicity below 30 μM and appeared to be an iron chelator
InChi: InChI=1S/C11H6F3NO2S/c12-11(13
DY-131 - CAS# 95167-41-2 60200 5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanoneDY131, also known as GSK 9089, CAS No. 95167 41 2, is a novel selective agonist at estrogen related receptors ERR and ERR. DY131 could potentiate the ERRgamma induced growth inhibition in LNCaP ERRgamma and DU145 ERRgamma cells in a dose dependent manner. ERRgamma may perform an antiproliferative or tumor suppressing function in prostate cancer cells. ERRgamma could be a novel therapeutic target for prostate cancer treatment. Product information CAS
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