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PDE2/PDE10-IN-1 is a phosphodiesterase 2 (PDE2) and PDE10 inhibitor with IC50s of 29 and 480 nM
4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38
an aporphine alkaloid found in Acoruscalamus
CPI-169 also suppresses cell growth with GI50 of <5 μM
CB-1158 Size:Contact [email protected] for quotation PDE2/PDE10-IN-1 is a phosphodiesterase 2CB 1158 (INCB01158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno oncology agent. Product information CAS Number: 2095732 06 0 Molecular Weight: 287. 12 Formula: C11H22BN3O5 Chemical Name: (3R,4S) 3 amino 1 [(2S) 2 aminopropanoyl] 4 [3 (dihydroxyboranyl)propyl]pyrrolidine 3 carboxylic acid Smiles:
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