YKL-05-099 Catalog No.:M11414-10 COC1=CC2=NC=NC(NC3=CC(Cl)=C(F)C=C3)=C2C=C1OCCCN1CCOCC1

COC1=CC2=NC=NC(NC3=CC(Cl)=C(F)C=C3)=C2C=C1OCCCN1CCOCC1

6'R)-6-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)-3H-spiro[2-benzofuran-1

It did not significantly inhibit tumorsphere formation in the breast cancer cell line SUM159

or 300 mg/kg twice per week in subcutaneous xenografts of KARPAS-422 and Pfeiffer cells

YKL-05-099 Catalog No.:M11414-10 COC1=CC2=NC=NC(NC3=CC(Cl)=C(F)C=C3)=C2C=C1OCCCN1CCOCC1YKL 05 099 is a selective inhibitor of Salt Inducible Kinase (SIK). Product information CAS Number: 1936529 65 5 Molecular Weight: 600. 11 Formula: C32H34ClN7O3 Chemical Name: 3 (2 Chloro 6 methylphenyl) 7 ((2 methoxy 4 (1 methylpiperidin 4 yl)phenyl)amino) 1 (5 methoxypyridin 2 yl) 3, 4 dihydropyrimido[4, 5 d]pyrimidin 2(1H) one Smiles: CN1CCC(CC1)C1=CC(OC)=C(C=C1)NC1=NC2=C(CN(C(=O)N2C2=CC=C(C=N2)OC)C2=C(Cl)C=CC=C2C)C=N1 InChiKey: VQINULODWGEVBB