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and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts
InChi: InChI=1S/C25H20N4O/c1-29-16-23(18-12-14-26-15-13-18)25(28-29)20-7-10-22(11-8-20)30-17-21-9-6-19-4-2-3-5-24(19)27-21/h2-16H
5-dimethyl-1H-imidazol-4-yl]ethynyl}pyridine
23)14-5-4-8-20-11-14
Fangchinoline - CAS# 436-77-1 Catalog No.:M12401-10 and inhibits RANKL-mediated MAPK andFangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti inflammatory sterilization and anti atherosclerosis. Fangchinoline, a novel HIV 1 inhibitor, inhibits HIV 1 replication by impairing gp160 proteolytic processing. Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK mediated signaling pathway in tumor cells which highly expressed FAK. Fangchinoline induces apoptosis
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