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47)22-11-12-22)39-28(42)25-15-21(49-29-24-14-20(36)10-13-23(24)26(48-8)17-37-29)18-41(25)30(43)27(33(2
Chemical Name: (3Z)-N-(3-Chlorophenyl)-3-[[3
and efficacious in a KRAS mutant xenograft model
CAS Number: 22978-25-2
Betulinic acid - CAS# 472-15-1 Catalog No.:M10557-10 47)22-11-12-22)39-28(42)25-15-21(49-29-24-14-20(36)10-13-23(24)26(48-8)17-37-29)18-41(25)30(43)27(33(2Betulinic acid is a pentacyclic lupane type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic
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