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InChi: InChI=1S/C17H14Cl2F2N4OS/c1-8(2)16(26)23-17-22-7-13(27-17)12-6-11(15(20)21)24-25(12)14-9(18)4-3-5-10(14)19/h3-8
CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4
BDBM50242403
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo
SB939 ties InChi: InChI=1S/C17H14Cl2F2N4OS/c1-8(2)16(26)23-17-22-7-13(27-17)12-6-11(15(20)21)24-25(12)14-9(18)4-3-5-10(14)19/h3-8SB939, is an orally bioavailable, small molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis.
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