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LP-184 490olCDE-IN-2 Sarecycline hydrochloride interferes with tRNA

SKU: 83053165696

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Description

Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome

Irisflorentin (10-40 μM) concentration-dependently suppresses LPS-induced p38 and ERK1/2 phosphorylation in a concentration-dependent manner

Smiles: CC(CCC(OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)C(C)(C)O)C1CCC2(C)C3CC=C4C(CCC(O)C4(C)C)C3(C)C(O)CC21C

InChiKey: XCIGZBVOUQVIPI-UHFFFAOYSA-N

LP-184 490olCDE-IN-2 Sarecycline hydrochloride interferes with tRNALP 184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP 184 has potent anti cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2). Product information CAS Number: 924835 67 6 Molecular Weight: 304. 34 Formula: C16H20N2O4 Chemical Name: 1 hydroxy 1 {[(6'R) 6' hydroxy 2',4',6' trimethyl 7' oxo 6',7' dihydrospiro[cyclopropane 1,5' inden] 3' yl]methyl}urea Smiles:

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