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2004 Feb 9
also known as GS-9620
Formula: C25H15FN4O2S
05%)-treated eyes show significant reduction of IOP between 2 and 7 hours after topical administration
TAS-119 4028 2004 Feb 9TAS 119 is a potent, selective and orally active Aurora A inhibitor with an IC50 of 1. 0 nM. TAS 119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS 119 has potent antitumor activites. Product information CAS Number: 1453099 83 6 Molecular Weight: 506. 36 Formula: C23H22Cl2FN5O3 Chemical Name: 1 (2,3 dichlorobenzoyl) 4 ({5 fluoro 6 [(5 methyl 1H pyrazol 3 yl)amino]pyridin 2 yl}methyl)piperidine 4
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