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A concentration-dependent inhibitory effect is observed with IC50 of 454 nM
5R)-2-{6-amino-8-[({[1
Carfilzomib-dependent selective inhibition of the chymotrypsin-like activity of the proteasome leads to antitumor activity in Waldenstrom's Macroglobulinemia
InChi: InChI=1S/C23H22N8O
MAO-IN-M30 dihydrochloride rdU A concentration-dependent inhibitory effect isMAO IN M30 dihydrochloride is an orally active, brain permeable, and brain selective irreversible MAO A (IC50=37 nM) and MAO B (IC50=57 nM) inhibitor. MAO IN M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO IN M30 dihydrochloride has a neuroprotective effect against Dexamethasone induced brain cell apoptosis. MAO IN M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's
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