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OSU-T315 - CAS# 2070015-22-2 Size:10mg solid InChiKey: JZAFPDYXTYKEQB-UHFFFAOYSA-N

SKU: 83693099072

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Description

InChiKey: JZAFPDYXTYKEQB-UHFFFAOYSA-N

CAS Number: 1221186-53-3

8 nM (hCCR2) and 7

CAS Number: 139298-40-1

OSU-T315 - CAS# 2070015-22-2 Size:10mg solid InChiKey: JZAFPDYXTYKEQB-UHFFFAOYSA-NOSU T315 (ILK IN 1) is a small Integrin linked kinase (ILK) inhibitor with an IC50 of 0. 6 M, inhibiting PI3K AKT signaling by dephosphorylation of AKT Ser473 and other ILK targets (GSK 3 and myosin light chain). OSU T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase dependent apoptosis in an ILK independent manner[2]. OSU T315 causes cell death through apoptosis and autophagy. Product information CAS

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