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BMS CCR2 22 yranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] AB928 shows rescue of these

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Description

AB928 shows rescue of these gene expression changes

4r)-4-(2-((2-cyclopropylethyl)amino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2

Smiles: CC1=CC(=CC=N1)C1=NC=C(CNC(=O)C2=CC=C3C(=C2)NC2=CC=CC=C32)C=C1F

7-dimethoxy-2-methyl-1

BMS CCR2 22 yranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] AB928 shows rescue of theseBMS CCR2 22 is a potent, specific and high affinity CC type chemokine receptor 2 (CCR2) antagonist with excellent binding affinity (binding IC50 of 5. 1 nM) and potent functional antagonism (calcium flux IC50 of 18 nM and chemotaxis IC50 of 1 nM). Product information CAS Number: 445479 97 0 Molecular Weight: 593. 66 Formula: C28H34F3N5O4S Chemical Name: 4 (methylsulfanyl) N [(1R,2S) 2 {2 [(2 {[(propan 2 yl)carbamoyl]amino} 5

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