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It inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression
PubMed PMID: 30271980
3-Bromopyruvate inhibits cell growth and induces apoptosis through interfering with glycolysis
InChi: InChI=1S/C16H19N5S/c1-11-14-15(22-13-6-4-3-5-12(13)18-14)19-16(17-11)21-9-7-20(2)8-10-21/h3-6
(R)-ADX-47273 nylacetate It inhibits hypoxia-induced HIF-1α transcriptional(R) ADX 47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . Product information CAS Number: 851881 59 9 Molecular Weight: 369. 36 Formula: C20H17F2N3O2 Chemical Name: (3R) 1 (4 fluorobenzoyl) 3 [3 (4 fluorophenyl) 1,2,4 oxadiazol 5 yl]piperidine Smiles: O=C(C1C=CC(F)=CC=1)N1C[C@@H](CCC1)C1=NC(=NO1)C1C=CC(F)=CC=1 InChiKey: VXQCCZHCFBHTTD OAHLLOKOSA N InChi: InChI=1S C20H17F2N3O2 c21 16 7 3 13(4 8 16)18 23
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