PIM1-IN-1 Size:Contact [email protected] for quotation and wild type (WT) cell

and wild type (WT) cell line LoVo with IC50s of 45

CAS Number: 146535-11-7

in mice bearing large established B16F10 tumors

GABAA receptors are GABA -gated chloride channels involved in mediating neuronal inhibition in the brain

PIM1-IN-1 Size:Contact [email protected] for quotation and wild type (WT) cellPIM1 IN 1 is a potent and highly selective PIM1 3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1 IN 1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti cancer activity. Product information CAS Number: 1417630 95 5 Molecular Weight: 474. 56 Formula: C25H30N8O2 Chemical Name: 2 [10 (2 methoxyethyl)