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InChiKey: LUJMEECXHPYQOF-UHFFFAOYSA-N
S-methyl DM1 is the primary cellular or liver metabolite of antibody-maytansinoid conjugates prepared with thiol-containing maytansinoids DM1
3R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}acetamido)-3-carboxypropanamido]-3-carbamoylpropanamido]propanamido]-3-hydroxybutanoyl]pyrrolidin-2-yl]formamido}-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S
SGCGAK-1 (0
SAH-SOS1A dehydroandrographolide InChiKey: LUJMEECXHPYQOF-UHFFFAOYSA-NSAH SOS1A is a peptide based SOS1 KRAS protein interaction inhibitor. SAH SOS1A binds to wild type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106 175 nM), directly and independently blocks nucleotide association, impairs KRAS driven cancer cell viability, and exerts its effects by on mechanism blockade of the ERK MAPK phosphosignaling cascade downstream of KRAS. Product information CAS Number: 1652561 87 9