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In vivo GNF-7 showed good efficacy in a xenotransplantation model and activity against primary AML patient samples
Smiles: C[C@H](NC(=O)CNC(=O)C1=CC(Cl)=CC=C1)C1C=CC=CC=1
induced by Bz-ATP with an IC50 of 13
BCN or other Alkyne group through click chemistry
KN-93 Phosphate - CAS# 1188890-41-6 Catalog No.:M6714-2 In vivo GNF-7 showed goodKN 93 Phosphate, CAS No. 1188890 41 6, is a CaMKII inhibitor. KN 93 suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR. KN 93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer. KN 93 ameliorates levodopa induced dyskinesia in a rat model of Parkinson's disease. KN 93 protects rat cerebral cortical neurons from N methyl D aspartic acid induced injury. Product