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A-887826 Catalog No.:M18746-C In vitro characterization of SLV308

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Description

In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone

and causes both the accumulation of single and double strand DNA breaks and the induction of apoptosis

with ED50 of 23 nM in the peptidergic caudodorsal neurons

It selectively displaces [3H]clozapine from DREADDs in vivo

A-887826 Catalog No.:M18746-C In vitro characterization of SLV308A 887826 is a potent, selective, oral bioavailable and voltage dependent Na(v)1. 8 sodium channel blocker with an IC50 of 11 nM . A 887826 attenuates neuropathic tactile allodynia in vivo. Product information CAS Number: 1266212 81 0 Molecular Weight: 480. 99 Formula: C26H29ClN4O3 Chemical Name: 5 (4 butoxy 3 chlorophenyl) N {[2 (morpholin 4 yl)pyridin 3 yl]methyl}pyridine 3 carboxamide Smiles:

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