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Ac-DEVD-CMK significantly blocked neurotoxicity at 24 hr after 1 hr of SIN-1 exposure and also protected against neurotoxicity at 24 hr after 90 min of zinc (75 μM) exposure
with an IC50 of 5 nM for inhibiting the autophosphorylation of p210Bcr-Abl
PubMed PMID: 27027150
InChiKey: ZMMKVDBZTXUHFO-UHFFFAOYSA-M
3-Chlorodiphenylamine purity E Ac-DEVD-CMK significantly blocked neurotoxicity at3 Chlorodiphenylamine is a high affinity Ca2+ sensitizer of cardiac muscle. 3 Chlorodiphenylamine is based on diphenylamine and binds to the isolated N domain of cardiac troponin C (cTnC) (Kd=6 M). 3 Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca2+ sensitizing compounds due to its small size, and can be used for systolic heart failure research. Product information CAS Number: 101 17 7 Molecular Weight: 203.
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