(E/Z)-Eltrombopag 13C 801uercetin 3 7-dimethyl ether BML-284 induces TCF-dependent transcriptional activity

BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM

as well as RET-dependent intracellular signaling

at anti-LID doses

OC1=CC2CC[C@H]3NCC4=CC=CC=C4[C@@H]3C=2C=C1O

(E/Z)-Eltrombopag 13C 801uercetin 3 7-dimethyl ether BML-284 induces TCF-dependent transcriptional activity(E Z) Eltrombopag 13C ((E Z) SB 497115 13C) is a mixture complex of E Eltrombopag and Z Eltrombopag, with 13C labeled. Z Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia. Product information CAS Number: 1217230 31 3 Molecular Weight: 446. 44 Formula: C25H22N4O4 Chemical Name: 3' {2 [2 (3,4 dimethylphenyl) 5 (C)methyl 3 oxo 2,3 dihydro(3,4,5 C) 1H pyrazol 4 yl]diazen 1 yl} 2' hydroxy